Tag Archives: Postpartum

Oral Allopregnanolone Analogue for Postpartum Depression Treatment

In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of postpartum depression (PPD).  SAGE-547, now called brexanolone, is a neurosteroid, an analogue of allopregnanolone and an allosteric modulator of GABAA receptors.  Since that time, Sage Therapeutics has conducted three randomized controlled trials, enrolling a total of 247 women diagnosed… Read More »

Maternal Programming During Pregnancy Induces Long-Term Postpartum Obesity

In mouse study, researchers find it’s not the added calories but the long-term reduction in energy expended During normal pregnancy, mothers always gain body weight within a proper range. However, many women worry that extra pounds put on during pregnancy will not be lost after childbirth and, in fact, past studies have shown that excessive… Read More »

Postpartum Care in the United States: Some Progress But Still So Far to Go

Earlier this year the American College of Obstetricians and Gynecologists (ACOG) released a revised Committee Opinion calling for a new paradigm for postpartum care in the United States.  Moving away from the single postpartum check at 6 weeks, ACOG has made a significant change in its recommendations for postpartum care: “All women should ideally have… Read More »